2418779-48-1
2418779-48-1
Chemical Structure
Antibacterial agent 254
- CAS No.: 2418779-48-1
- Formula:C13H15NO4
- Molecular Weight:249.26
InChIKey: XIKNZILHTTURQV-GHMZBOCLSA-N
SMILES: OC(C1=CC(CC(N[C@@H]2CC[C@H]2O)=O)=CC=C1)=O
Biological Activity: Antibacterial agent 254 (Compound 2) is a dispersion sensor (DspS) activator that disperses Pseudomonas aeruginosa biofilms. Antibacterial agent 254 can dislodge 7-day P. aeruginosa biofilms at 50 μM. Antibacterial agent 254 also enhances the effects of Ciprofloxacin (HY-B0356) against P. aeruginosa and increases the expression of matrix-degrading enzyme genes pelA, pslG and eddA[1].
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Antibacterial agent 254 | Antibacterial agent 254 (Compound 2) is a dispersion sensor (DspS) activator that disperses Pseudomonas aeruginosa biofilms. Antibacterial agent 254 can dislodge 7-day P. aeruginosa biofilms at 50 μM. Antibacterial agent 254 also enhances the effects of Ciprofloxacin (HY-B0356) against P. aeruginosa and increases the expression of matrix-degrading enzyme genes pelA, pslG and eddA. | |||||||||||||||||||||
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