2419107-09-6
2419107-09-6
Chemical Structure
Aurora kinase inhibitor-9
- CAS No.: 2419107-09-6
- Formula:C19H17Cl2N3O4S
- Molecular Weight:454.33
IUPAC Name: ethyl 5,7-dichloro-4-((3-(N-methylsulfamoyl)phenyl)amino)quinoline-3-carboxylate
InChIKey: SWOMTHLQJFJUKX-UHFFFAOYSA-N
SMILES: CCOC(C1=C(C2=C(C=C(C=C2N=C1)Cl)Cl)NC3=CC(S(=O)(NC)=O)=CC=C3)=O
Biological Activity: Aurora kinase inhibitor-9 (compound 9d) is a potent AURKA/B dual aurora kinase inhibitor with IC50s of 0.093, 0.09 µM for Aurora A, Aurora B, respectively. Aurora kinase inhibitor-9 shows broad spectrum anti-proliferative activity[1].
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Aurora kinase inhibitor-9 | Aurora kinase inhibitor-9 (compound 9d) is a potent AURKA/B dual aurora kinase inhibitor with IC50s of 0.093, 0.09 µM for Aurora A, Aurora B, respectively. Aurora kinase inhibitor-9 shows broad spectrum anti-proliferative activity. | |||||||||||||||||||||
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