2419107-97-2
2419107-97-2
Chemical Structure
NF-κB/PON1-IN-1
- CAS No.: 2419107-97-2
- Formula:C20H16N6O4S2
- Molecular Weight:468.51
IUPAC Name: 2-((4-oxo-3-(4-sulfamoylphenyl)-3,4-dihydroquinazolin-2-yl)thio)-N-(pyrazin-2-yl)acetamide
InChIKey: QTWSOVMUMKGXFF-UHFFFAOYSA-N
SMILES: O=C(NC1=NC=CN=C1)CSC(N2C3=CC=C(S(=O)(N)=O)C=C3)=NC4=C(C=CC=C4)C2=O
Biological Activity: NF-κB/PON1-IN-1 (Compound 16) is a NF-κB/PON1 pathway inhibitor. NF-κB/PON1-IN-1 has antioxidant (IC50 = 45.76 µM) and hepatoprotective activities[1].
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NF-κB/PON1-IN-1 | NF-κB/PON1-IN-1 (Compound 16) is a NF-κB/PON1 pathway inhibitor. NF-κB/PON1-IN-1 has antioxidant (IC50 = 45.76 µM) and hepatoprotective activities. | |||||||||||||||||||||
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