242138-07-4
242138-07-4
Chemical Structure
Omalizumab
Synonym(s): Olizumab; rhuMab-E25; IGE25; RG-3648
- CAS No.: 242138-07-4
- Formula:N/A
- Molecular Weight:(146.46 kDa)
SMILES: [Omalizumab]
Biological Activity: Omalizumab is a recombinant, humanized, monoclonal antibody against human immunoglobulin E (IgE) with a KD of 0.393 nM. Omalizumab binds to the human FcγRIIb receptors with a KD of 6.37 uM. Omalizumab has the potential for persistent allergic asthma research[1][2].
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Omalizumab | 99.7% | Omalizumab is a recombinant, humanized, monoclonal antibody against human immunoglobulin E (IgE) with a KD of 0.393 nM. Omalizumab binds to the human FcγRIIb receptors with a KD of 6.37 uM. Omalizumab has the potential for persistent allergic asthma research. | ||||||||||||||||||||
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References
- [1]. Peipei Liu, et al. An Omalizumab Biobetter Antibody With Improved Stability and Efficacy for the Treatment of Allergic Diseases. Front Immunol. 2020 Nov 27;11:596908. [Content Brief]
- [2]. Seung Y Chu, et al. Reduction of total IgE by targeted coengagement of IgE B-cell receptor and FcγRIIb with Fc-engineered antibody. J Allergy Clin Immunol. 2012 Apr;129(4):1102-15. [Content Brief]
