2428400-07-9
2428400-07-9
Chemical Structure
Amino-PEG7-t-butyl ester
- CAS No.: 2428400-07-9
- Formula:C21H43NO9
- Molecular Weight:453.57
IUPAC Name: tert-butyl 1-amino-3,6,9,12,15,18,21-heptaoxatetracosan-24-oate
InChIKey: DQPAYUNKPDINFW-UHFFFAOYSA-N
SMILES: O=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCOCCN
Biological Activity: Amino-PEG7-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Amino-PEG7-t-butyl ester is a PEG reagent containing an amino NH2 group with a t-butyl protected carboxyl group (Boc). Amino-PEG7-t-butyl ester can be used in drug delivery research[2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Amino-PEG7-t-butyl ester | 99.77% | Amino-PEG7-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Amino-PEG7-t-butyl ester is a PEG reagent containing an amino NH2 group with a t-butyl protected carboxyl group (Boc). Amino-PEG7-t-butyl ester can be used in drug delivery research. | ||||||||||||||||||||
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Propargyl-PEG7-Boc | Propargyl-PEG7-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG7-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | |||||||||||||||||||||
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NH2-PEG6-Boc | 98.0% | NH2-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. NH2-PEG6-Boc is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | ||||||||||||||||||||
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m-PEG7-Boc | m-PEG7-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. | |||||||||||||||||||||
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Azido-PEG7-t-butyl ester | Azido-PEG7-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG7-t-butyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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Bromo-PEG7-Boc | Bromo-PEG7-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. | |||||||||||||||||||||
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Amino-PEG9-Boc | 99.90% | Amino-PEG9-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. | ||||||||||||||||||||
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Hydroxy-PEG7-Boc | Hydroxy-PEG7-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. | |||||||||||||||||||||
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m-PEG8-T-Butyl ester | m-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. | |||||||||||||||||||||
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Amino-PEG8-Boc | 99.96% | Amino-PEG8-Boc is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG8-Boc is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. | ||||||||||||||||||||
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Acid-PEG7-t-butyl ester | 99.82% | Acid-PEG7-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. | ||||||||||||||||||||
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References
- [1]. Rosario Pignatello, et al. New Amphiphilic Conjugates of Amino–Poly(ethylene glycols) With Lipoamino Acids as Surface Modifiers of Colloidal Drug Carriers. Macromolecular Chemistry and Physics. 15 November 2012.
- [2]. Li H, et al. Discovery of Pentacyclic Triterpenoid PROTACs as a Class of Effective Hemagglutinin Protein Degraders. J Med Chem. 2022 May 26;65(10):7154-7169. [Content Brief]
