2436760-81-3
Chemical Structure
Befiradol hydrochloride
Synonym(s): NLX-112 hydrochloride; F 13640 hydrochloride
- CAS No.: 2436760-81-3
- Formula:C20H23Cl2F2N3O
- Molecular Weight:430.32
IUPAC Name: (3-chloro-4-fluorophenyl)(4-fluoro-4-((((5-methylpyridin-2-yl)methyl)amino)methyl)piperidin-1-yl)methanone hydrochloride
InChIKey: MEFWJLIGVNWMAB-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(F)C(Cl)=C1)N2CCC(CNCC3=NC=C(C)C=C3)(F)CC2.Cl
Biological Activity: Befiradol (NLX-112) hydrochloride is a highly selective 5-HT1A receptor agonist that acts on both presynaptic and postsynaptic sites. Befiradol hydrochloride attenuates sedative agent-induced respiratory depression in neonatal and adult rats. Befiradol reduces the duration of sedative agent-induced analgesia and sedation in adult rats. Befiradol hydrochloride can be used in studies related to opioid-induced respiratory depression[1].
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Befiradol hydrochloride | 98.80% | Befiradol (NLX-112) hydrochloride is a highly selective 5-HT1A receptor agonist that acts on both presynaptic and postsynaptic sites. Befiradol hydrochloride attenuates sedative agent-induced respiratory depression in neonatal and adult rats. Befiradol reduces the duration of sedative agent-induced analgesia and sedation in adult rats. Befiradol hydrochloride can be used in studies related to opioid-induced respiratory depression. | ||||||||||||||||||||
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