2445277-57-4
2445277-57-4
Chemical Structure
Antifungal agent 33
- CAS No.: 2445277-57-4
- Formula:C21H14ClN5O3
- Molecular Weight:419.82
IUPAC Name: (E)-N'-(4-chlorobenzylidene)-2-(4-nitrophenyl)-1H-benzo[d]imidazole-5-carbohydrazide
InChIKey: KMSMQKLBYVCZSK-FSJBWODESA-N
SMILES: O=C(C1=CC=C2C(N=C(C3=CC=C([N+]([O-])=O)C=C3)N2)=C1)N/N=C/C4=CC=C(Cl)C=C4
Biological Activity: Antifungal agent 33 (compound 4e) is a potent antifungal agent. Antifungal agent 33 exhibits remarkable antifungal activity against C. albicans, with a MIC of 16 μg/mL. Antifungal agent 33 shows potent inhibitory activity against Lanosterol 14α-demethylase (CYP51), with an IC50 of 0.19 μg/mL[1].
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Antifungal agent 33 | Antifungal agent 33 (compound 4e) is a potent antifungal agent. Antifungal agent 33 exhibits remarkable antifungal activity against C. albicans, with a MIC of 16 μg/mL. Antifungal agent 33 shows potent inhibitory activity against Lanosterol 14α-demethylase (CYP51), with an IC50 of 0.19 μg/mL. | |||||||||||||||||||||
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