2445499-20-5
2445499-20-5
Chemical Structure
JAK-IN-21
- CAS No.: 2445499-20-5
- Formula:C19H16N8O
- Molecular Weight:372.38
IUPAC Name: N-(cyanomethyl)-4-(2-((1-(cyanomethyl)-1H-pyrazol-4-yl)amino)-5-methylpyrimidin-4-yl)benzamide
InChIKey: HTJNRNRPDXBRQY-UHFFFAOYSA-N
SMILES: N#CCNC(C1=CC=C(C2=NC(NC3=CN(CC#N)N=C3)=NC=C2C)C=C1)=O
Biological Activity: JAK-IN-21 (Example 4) is a selective and potent JAK inhibitor with IC50s of 1.73, 2.04, 109 and 62.9 nM against JAK1, JAK2, J2V617F and TYK2, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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JAK-IN-21 | 99.72% | JAK-IN-21 (Example 4) is a selective and potent JAK inhibitor with IC50s of 1.73, 2.04, 109 and 62.9 nM against JAK1, JAK2, J2V617F and TYK2, respectively. | ||||||||||||||||||||
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