2446880-46-0

ND-011992 Chemical Structure
2446880-46-0

Chemical Structure

ND-011992

  • CAS No.: 2446880-46-0
  • Formula:C21H14F3N3O
  • Molecular Weight:381.35

InChIKey: CAIODVXPWNFDFE-UHFFFAOYSA-N

SMILES: FC(F)(F)C(C=C1)=CC=C1OC(C=C2)=CC=C2NC3=NC=NC4=CC=CC=C43

Biological Activity: ND-011992 is a reversible, selective quinazoline-type inhibitor targeting quinone reductases and quinol oxidases. ND-011992 inhibits respiratory complex I and bo3 oxidase in addition to bd-I and bd-II oxidases in E. coli strain BL21*Δcyo with the IC50 of 0.12, 2.47, 0.63 and 1.3 μM, respectively. ND-011992 can be used for tuberculosis study[1].

Cat. No. Product Name Purity Description Pricing
HY-155107
ND-011992 98.03% ND-011992 is a reversible, selective quinazoline-type inhibitor targeting quinone reductases and quinol oxidases. ND-011992 inhibits respiratory complex I and bo3 oxidase in addition to bd-I and bd-II oxidases in E. coli strain BL21*Δcyo with the IC50 of 0.12, 2.47, 0.63 and 1.3 μM, respectively. ND-011992 can be used for tuberculosis study.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References