2448519-26-2
2448519-26-2
Chemical Structure
TP0591816
- CAS No.: 2448519-26-2
- Formula:C27H31ClN6O4
- Molecular Weight:539.03
IUPAC Name: (22S,E)-45-chloro-15-((1r,3S)-3-hydroxycyclobutyl)-11-methyl-5-oxa-8,11-diaza-1(2,7)-pyrazolo[1,5-a]pyrimidina-2(2,1)-piperidina-4(1,2)-benzenacycloundecaphane-3,7-dione
InChIKey: HIRKVDNSABOJID-ZJBJCVSYSA-N
SMILES: CN1C2=CC([C@]3([H])C[C@H](C3)O)=NC4=CC([C@@]5([H])N(CCCC5)C(C6=CC(Cl)=CC=C6OCC(NCC1)=O)=O)=NN24
Biological Activity: TP0591816 is a potent dual inhibitor of wild-type and mutant respiratory syncytial virus fusion proteins (wild-type, EC50 = 0.27 nM; D486N-mutant, EC50 = 0.70 nM).
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TP0591816 | TP0591816 is a potent dual inhibitor of wild-type and mutant respiratory syncytial virus fusion proteins (wild-type, EC50 = 0.27 nM; D486N-mutant, EC50 = 0.70 nM). | |||||||||||||||||||||
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