2454680-16-9
Chemical Structure
Cap-dependent endonuclease-IN-8
- CAS No.: 2454680-16-9
- Formula:C29H23F2N3O6S
- Molecular Weight:579.57
IUPAC Name: (((6aR,7S,10R)-6-((S)-7,8-difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-yl)-2,12-dioxo-2,6,6a,7,10,12-hexahydro-7,10-methanodipyrido[2,1-c:2',1'-f][1,2,4]triazin-1-yl)oxy)methyl methyl carbonate
InChIKey: KTKPRWQWDFILGH-ZVNBPAIVSA-N
SMILES: O=C1N2[C@]([C@H]3C[C@@H]2C=C3)([H])N([C@@]4([H])C5=CC=C(F)C(F)=C5CSC6=CC=CC=C64)N7C1=C(C(C=C7)=O)OCOC(OC)=O
Biological Activity: Cap-dependent endonuclease-IN-8 is a potent inhibitor of cap-dependent endonuclease (CEN). Cap-dependent endonuclease-IN-8 inhibits replication of orthomyxoviruses (including influenza A, influenza B and influenza C) (extracted from patent CN111410661A, compound I-196)[1].
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Cap-dependent endonuclease-IN-8 | Cap-dependent endonuclease-IN-8 is a potent inhibitor of cap-dependent endonuclease (CEN). Cap-dependent endonuclease-IN-8 inhibits replication of orthomyxoviruses (including influenza A, influenza B and influenza C) (extracted from patent CN111410661A, compound I-196). | |||||||||||||||||||||
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