2456295-45-5
2456295-45-5
Chemical Structure
Keap1-Nrf2-IN-15
- CAS No.: 2456295-45-5
- Formula:C39H35N3O12S2
- Molecular Weight:801.84
IUPAC Name: 2,2'-((2-(3-(1,3-dioxoisoindolin-2-yl)propyl)naphthalene-1,4-diyl)bis(((4-methoxyphenyl)sulfonyl)azanediyl))diacetic acid
InChIKey: NRGDPQSGSQBMPD-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)S(=O)(N(C2=CC(CCCN3C(C4=C(C3=O)C=CC=C4)=O)=C(C5=CC=CC=C52)N(S(=O)(C6=CC=C(C=C6)OC)=O)CC(O)=O)CC(O)=O)=O
Biological Activity: Keap1-Nrf2-IN-15 (Compound 24a) is a potent Keap1-Nrf2 protein-protein interaction inhibitor with IC50s of 77 nM and 2.5 nM in FP assay and TR-FRET assay, respectively[1].
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Keap1-Nrf2-IN-15 | Keap1-Nrf2-IN-15 (Compound 24a) is a potent Keap1-Nrf2 protein-protein interaction inhibitor with IC50s of 77 nM and 2.5 nM in FP assay and TR-FRET assay, respectively. | |||||||||||||||||||||
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