2456309-77-4
2456309-77-4
Chemical Structure
IDO1-IN-32
- CAS No.: 2456309-77-4
- Formula:C26H29Cl2FN4O3
- Molecular Weight:535.44
InChIKey: MZGIYKQGFMQNQO-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CN1C2=CC(NC(NC3=CC=C(Cl)C=C3F)=O)=C(N(CC(C)C)CC(C)C)C(Cl)=C2)O
Biological Activity: IDO1-IN-32 (Compound 45) is a potent and orally effective IDO1 inhibitor with an IC50 of 10 pM. IDO1-IN-32 exhibits significant anti-proliferative activity against Hela cells. IDO1-IN-32 can significantly inhibit tumor growth in CT26 and LCC transplanted mouse models by activating anti-tumor immunity. IDO1-IN-32 can be used for research on colon cancer and breast cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
IDO1-IN-32 | IDO1-IN-32 (Compound 45) is a potent and orally effective IDO1 inhibitor with an IC50 of 10 pM. IDO1-IN-32 exhibits significant anti-proliferative activity against Hela cells. IDO1-IN-32 can significantly inhibit tumor growth in CT26 and LCC transplanted mouse models by activating anti-tumor immunity. IDO1-IN-32 can be used for research on colon cancer and breast cancer. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
