24568-67-0
Chemical Structure
Elsinochrome A
- CAS No.: 24568-67-0
- Formula:C30H24O10
- Molecular Weight:544.51
IUPAC Name: 2-bromo-3-chloro-6,7-dihydropyrazolo[1,5-a]pyrimidin-5(4H)-one
InChIKey: WTZSLZBEQHGTRK-HZPDHXFCSA-N
SMILES: CC([C@H]1C(C2=C(C3=C(C=C4OC)O)C4=C(C(OC)=CC(O)=C56)C5=C2C([C@@H]1C(C)=O)=C(OC)C6=O)=C(OC)C3=O)=O
Biological Activity: Elsinochrome A is a perylene quinone photosensitizer, and can generate reactive oxygen species (ROS) to induce apoptosis and autophagy under light excitation. Elsinochrome A also shows antifungal activity against C. albicans biofilm through photodynamic antimicrobial chemotherapy (PACT). Elsinochrome A can be used for research of photodynamic therapy (PDT) (Ex: 460 nm)[1][2].
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Elsinochrome A | Elsinochrome A is a perylene quinone photosensitizer, and can generate reactive oxygen species (ROS) to induce apoptosis and autophagy under light excitation. Elsinochrome A also shows antifungal activity against C. albicans biofilm through photodynamic antimicrobial chemotherapy (PACT). Elsinochrome A can be used for research of photodynamic therapy (PDT) (Ex: 460 nm). | |||||||||||||||||||||
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References
- [1]. Yao Y, et al. Elsinochrome A induces cell apoptosis and autophagy in photodynamic therapy. J Cell Biochem. 2023 Sep;124(9):1346-1365. [Content Brief]
- [2]. Pan L, et al. Inhibitory Effects and Mechanism of Action of Elsinochrome A on Candida albicans and Its Biofilm. J Fungi (Basel). 2022 Aug 11;8(8):841. [Content Brief]
