24579-14-4
24579-14-4
Chemical Structure
4'-Hydroxywarfarin
- CAS No.: 24579-14-4
- Formula:C19H16O5
- Molecular Weight:324.33
IUPAC Name: 4-hydroxy-3-(1-(4-hydroxyphenyl)-3-oxobutyl)-2H-chromen-2-one
InChIKey: RRZWAMPDGRWRPF-UHFFFAOYSA-N
SMILES: O=C1C(C(C2=CC=C(O)C=C2)CC(C)=O)=C(O)C3=CC=CC=C3O1
Biological Activity: 4′-Hydroxywarfarin is a regioisomeric phenolic derivative of Warfarin (HY-B0687). 4′-Hydroxywarfarin is a major metabolite of Warfarin in mammals and serves as a metabolic probe for the diversity of cytochrome P-450 isoenzymes[1][2].
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4'-Hydroxywarfarin | 99.59% | 4′-Hydroxywarfarin is a regioisomeric phenolic derivative of Warfarin (HY-B0687). 4′-Hydroxywarfarin is a major metabolite of Warfarin in mammals and serves as a metabolic probe for the diversity of cytochrome P-450 isoenzymes. | ||||||||||||||||||||
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4'-Hydroxywarfarin-d4 | 4'-Hydroxywarfarin-d4 is the deuterated-labeled 4'-Hydroxywarfarin (HY-139003). 4'-Hydroxywarfarin is a regioisomeric phenolic derivative of Warfarin (HY-B0687). 4'-Hydroxywarfarin is a major metabolite of Warfarin in mammals and serves as a metabolic probe for the diversity of cytochrome P-450 isoenzymes. | |||||||||||||||||||||
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References
- [1]. Nowak, Paweł M, et al. Modulation of pK a by cyclodextrins; subtle structural changes induce spectacularly different behaviors. RSC Adv., 5(95), 77545–77552.
- [2]. Rizzo JD, et al. Microbial models of mammalian metabolism: conversion of warfarin to 4'-hydroxywarfarin using Cunninghamella bainieri. Journal of pharmaceutical sciences. 1989 Mar;78(3):183-9.
