2460738-32-1
Chemical Structure
CT1-3
- CAS No.: 2460738-32-1
- Formula:C25H29NO3S2
- Molecular Weight:455.63
IUPAC Name: 5,5'-diallyl-2'-(2-((4-isothiocyanatobutyl)sulfinyl)ethoxy)-[1,1'-biphenyl]-2-ol
InChIKey: DCYRFSQCNZBYOA-UHFFFAOYSA-N
SMILES: OC1=CC=C(CC=C)C=C1C2=CC(CC=C)=CC=C2OCCS(CCCCN=C=S)=O
Biological Activity: CT1-3 is a potent anticancer agent. CT1-3 induces mitochondria-mediated apoptosis by regulating JNK/Bcl-2/Bax/XIAP pathway. CT1-3 suppresses the epithelial mesenchymal transition (EMT) potential of human cancer cells (HCCs) via regulating the E-cadherin/Snail axis, thus inhibits tumorigenesis. CT1-3 has a strong antitumor effect in mice model and exhibits no significant hepatic and renal toxicity[1].
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CT1-3 | CT1-3 is a potent anticancer agent. CT1-3 induces mitochondria-mediated apoptosis by regulating JNK/Bcl-2/Bax/XIAP pathway. CT1-3 suppresses the epithelial mesenchymal transition (EMT) potential of human cancer cells (HCCs) via regulating the E-cadherin/Snail axis, thus inhibits tumorigenesis. CT1-3 has a strong antitumor effect in mice model and exhibits no significant hepatic and renal toxicity. | |||||||||||||||||||||
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