2468046-72-0
2468046-72-0
Chemical Structure
BRM/BRG1 ATP-IN-8
- CAS No.: 2468046-72-0
- Formula:C26H23N5O6S2
- Molecular Weight:565.62
InChIKey: FIJALBFJFWBXFB-UHFFFAOYSA-N
SMILES: O=C(C1(CC1)C2=NC=CC(C3=CC=CC(C4=CSC(NC(CNC(C5=CN(S(=O)(C)=O)C=C5)=O)=O)=N4)=C3)=C2)O
Biological Activity: BRM/BRG1 ATP-IN-8 (Compound Cpd14) is an orally active BRG1/BRM ATPase domain inhibitor. BRM/BRG1 ATP-IN-8 exerts antitumor effects by disrupting aberrant chromatin remodeling in cancer cells, inducing apoptosis and growth arrest. BRM/BRG1 ATP-IN-8 is promising for research of BRG1/BRM-dependent malignancies, including hematological cancers, prostate cancer, breast cancer, and Ewing's sarcoma[1].
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BRM/BRG1 ATP-IN-8 | BRM/BRG1 ATP-IN-8 (Compound Cpd14) is an orally active BRG1/BRM ATPase domain inhibitor. BRM/BRG1 ATP-IN-8 exerts antitumor effects by disrupting aberrant chromatin remodeling in cancer cells, inducing apoptosis and growth arrest. BRM/BRG1 ATP-IN-8 is promising for research of BRG1/BRM-dependent malignancies, including hematological cancers, prostate cancer, breast cancer, and Ewing's sarcoma. | |||||||||||||||||||||
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