247037-81-6
247037-81-6
Chemical Structure
BAY39-5493
- CAS No.: 247037-81-6
- Formula:C17H15ClFN3O2S
- Molecular Weight:379.84
IUPAC Name: ethyl (R)-6-(2-chloro-4-fluorophenyl)-4-methyl-2-(thiazol-2-yl)-1,6-dihydropyrimidine-5-carboxylate
InChIKey: JIQRTJRFRXOOQE-AWEZNQCLSA-N
SMILES: O=C(C1=C(C)N=C(C2=NC=CS2)N[C@H]1C3=CC=C(F)C=C3Cl)OCC
Biological Activity: BAY39-5493 is a non-nucleoside inhibitor that inhibits HBV replication. BAY39-5493 inhibits viral DNA replication by preventing the formation of viral core particles (nucleocapsids). The IC50 value of BAY39-5493 against HBV in stably transfected HepG2.2.15 cells is 0.03 μM[1].
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BAY39-5493 | BAY39-5493 is a non-nucleoside inhibitor that inhibits HBV replication. BAY39-5493 inhibits viral DNA replication by preventing the formation of viral core particles (nucleocapsids). The IC50 value of BAY39-5493 against HBV in stably transfected HepG2.2.15 cells is 0.03 μM. | |||||||||||||||||||||
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