2475078-38-5
2475078-38-5
Chemical Structure
Cathepsin-IN-5
- CAS No.: 2475078-38-5
- Formula:C22H20N2O6S
- Molecular Weight:440.47
InChIKey: RHBUZXNTKZZXRU-ZPICJPFVSA-N
SMILES: O=C(C1=CC=C([N+]([O-])=O)O1)N[C@@H](CCC2=CC=CC=C2)/C=C/S(=O)(C3=CC=CC=C3)=O
Biological Activity: Cathepsin-IN-5 is a cathepsin inhibitor with IC50 values of 6.2 μM and 81 nM for cathepsin L and cathepsin S. Cathepsin-IN-5 inhibits cancer cells proliferation, induces apoptosis, reduces growth of hepatocellular tumors in mouse models, and modulates expression of genes linked to cell death, cell proliferation, and cellular processes. Cathepsin-IN-5 can be used for the research of hepatocellular carcinoma[1].
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Cathepsin-IN-5 | Cathepsin-IN-5 is a cathepsin inhibitor with IC50 values of 6.2 μM and 81 nM for cathepsin L and cathepsin S. Cathepsin-IN-5 inhibits cancer cells proliferation, induces apoptosis, reduces growth of hepatocellular tumors in mouse models, and modulates expression of genes linked to cell death, cell proliferation, and cellular processes. Cathepsin-IN-5 can be used for the research of hepatocellular carcinoma. | |||||||||||||||||||||
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