2477651-10-6
2477651-10-6
Chemical Structure
USP8-IN-3
- CAS No.: 2477651-10-6
- Formula:C18H18F3N5O2S
- Molecular Weight:425.43
IUPAC Name: 1-(4-nitrophenyl)-3-(1-(6-(trifluoromethyl)pyridin-2-yl)piperidin-4-yl)thiourea
InChIKey: DYHHEFBWFATDAN-UHFFFAOYSA-N
SMILES: [O-][N+](C1=CC=C(NC(NC2CCN(CC2)C3=CC=CC(C(F)(F)F)=N3)=S)C=C1)=O
Biological Activity: USP8-IN-3 (Compd U51) is a deubiquitinase USP8 inhibitor with an IC50 value of 4.0 μM. USP8-IN-3 also inhibits the proliferation of GH3 and H1957 cells with GI50s of 37.03 μM and 6.01 μM, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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USP8-IN-3 | 98.37% | USP8-IN-3 (Compd U51) is a deubiquitinase USP8 inhibitor with an IC50 value of 4.0 μM. USP8-IN-3 also inhibits the proliferation of GH3 and H1957 cells with GI50s of 37.03 μM and 6.01 μM, respectively. | ||||||||||||||||||||
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