2481484-51-7
2481484-51-7
Chemical Structure
COX-2/5-LOX-IN-3
- CAS No.: 2481484-51-7
- Formula:C17H16ClN3O2S
- Molecular Weight:361.85
IUPAC Name: N-(4-(4-chlorophenyl)-3-cyanothiophen-2-yl)-2-morpholinoacetamide
InChIKey: MOMYWNZOSHEDCN-UHFFFAOYSA-N
SMILES: O=C(NC1=C(C#N)C(C2=CC=C(Cl)C=C2)=CS1)CN3CCOCC3
Biological Activity: COX-2/5-LOX-IN-3 (compound 5b) is a potent and dual COX-2/5-LOX inhibitor with IC50 values of 45.73, 5.45 and 4.33 μM for COX-1, COX-2, and 5-LOX, respectively. COX-2/5-LOX-IN-3 has the potential for the research of inflammation diseases[1].
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COX-2/5-LOX-IN-3 | COX-2/5-LOX-IN-3 (compound 5b) is a potent and dual COX-2/5-LOX inhibitor with IC50 values of 45.73, 5.45 and 4.33 μM for COX-1, COX-2, and 5-LOX, respectively. COX-2/5-LOX-IN-3 has the potential for the research of inflammation diseases. | |||||||||||||||||||||
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