2482998-35-4
2482998-35-4
Chemical Structure
HDAC1-IN-3
- CAS No.: 2482998-35-4
- Formula:C22H24ClN7O2
- Molecular Weight:453.92
IUPAC Name: 2-(2-((6-cyano-1-methyl-1H-indol-3-yl)methyl)-2,6-diazaspiro[3.4]octan-6-yl)-N-hydroxypyrimidine-5-carboxamide hydrochloride
InChIKey: NPDHHPIUUWFZPB-UHFFFAOYSA-N
SMILES: O=C(C1=CN=C(N(CC2)CC32CN(CC4=CN(C)C5=C4C=CC(C#N)=C5)C3)N=C1)NO.[H]Cl
Biological Activity: HDAC1-IN-3 is a potent Pf HDAC1 inhibitor. HDAC1-IN-3 shows antimalarial activity in wild-type and multidrug-resistant parasite strains. HDAC1-IN-3 shows a significant in vivo killing effect against all life cycles of parasites[1].
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HDAC1-IN-3 | HDAC1-IN-3 is a potent Pf HDAC1 inhibitor. HDAC1-IN-3 shows antimalarial activity in wild-type and multidrug-resistant parasite strains. HDAC1-IN-3 shows a significant in vivo killing effect against all life cycles of parasites. | |||||||||||||||||||||
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