2485732-30-5
2485732-30-5
Chemical Structure
PAK1-IN-1
- CAS No.: 2485732-30-5
- Formula:C26H20ClN5O2
- Molecular Weight:469.92
IUPAC Name: 6-(2-chloro-4-(3-methyl-2-oxopyridin-1(2H)-yl)phenyl)-N-(pyridin-4-ylmethyl)-1H-indazole-3-carboxamide
InChIKey: POZJQDTZTIKKTO-UHFFFAOYSA-N
SMILES: CC1=CC=CN(C1=O)C2=CC=C(C(Cl)=C2)C3=CC=C4C(NN=C4C(NCC5=CC=NC=C5)=O)=C3
Biological Activity: PAK1-IN-1 is a potent and selective PAK1 inhibitor with an IC50 of 9.8 nM. PAK1-IN-1 inhibits the migration and invasion of PAK1-related tumour cells in a dose-dependent manner[1].
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PAK1-IN-1 | PAK1-IN-1 is a potent and selective PAK1 inhibitor with an IC50 of 9.8 nM. PAK1-IN-1 inhibits the migration and invasion of PAK1-related tumour cells in a dose-dependent manner. | |||||||||||||||||||||
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