2488788-52-7

RMC-0331 Chemical Structure
2488788-52-7

Chemical Structure

RMC-0331

Synonym(s): RM-023

  • CAS No.: 2488788-52-7
  • Formula:C22H25ClF3N5O3
  • Molecular Weight:499.91

IUPAC Name: (R)-(4-((1-(3-amino-5-(trifluoromethyl)phenyl)ethyl)amino)-2-chloro-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidin-6-yl)(4-methoxytetrahydro-2H-pyran-4-yl)methanone

InChIKey: HOBOGRTXXDLZIB-GFCCVEGCSA-N

SMILES: O=C(N1CC2=NC(Cl)=NC(N[C@@H](C3=CC(C(F)(F)F)=CC(N)=C3)C)=C2C1)C4(OC)CCOCC4

Biological Activity: RMC-0331 (RM-023) is a potent, selective and orally bioavailable SOS1 inhibitor. RMC-0331 is an in vivo tool compound that blocks RAS activation via disruption of the RAS-SOS1 interaction[1].

Cat. No. Product Name Purity Description Pricing
HY-134885
RMC-0331 98.96% RMC-0331 (RM-023) is a potent, selective and orally bioavailable SOS1 inhibitor. RMC-0331 is an in vivo tool compound that blocks RAS activation via disruption of the RAS-SOS1 interaction.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References