2489528-97-2
2489528-97-2
Chemical Structure
FLT3-IN-23
- CAS No.: 2489528-97-2
- Formula:C22H28F3N5O2
- Molecular Weight:451.49
InChIKey: VPEDGTIAOONCJZ-GASCZTMLSA-N
SMILES: CC1(COC1)COC2=CC=C(C=C2)NC3=NC=C(C(N[C@@H]4CC[C@H](N)CC4)=N3)C(F)(F)F
Biological Activity: FLT3-IN-23 (compound 15) is an inhibitor of JFMS-like tyrosine kinase 3 (FLT3) with an IC50 of 7.42 nM. FLT3-IN-23 has antiproliferative activities against BaF3 cells carrying various FLT3-TKD and FLT3-ITD-TKD mutations[1].
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FLT3-IN-23 | FLT3-IN-23 (compound 15) is an inhibitor of JFMS-like tyrosine kinase 3 (FLT3) with an IC50 of 7.42 nM. FLT3-IN-23 has antiproliferative activities against BaF3 cells carrying various FLT3-TKD and FLT3-ITD-TKD mutations. | |||||||||||||||||||||
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