2490284-25-6
2490284-25-6
Chemical Structure
NN-390
- CAS No.: 2490284-25-6
- Formula:C17H16F4N2O4S
- Molecular Weight:420.38
IUPAC Name: N-hydroxy-4-(((2,3,4,5-tetrafluoro-N-isopropylphenyl)sulfonamido)methyl)benzamide
InChIKey: SJWJGLIJTRUXIZ-UHFFFAOYSA-N
SMILES: O=C(NO)C1=CC=C(CN(C(C)C)S(=O)(C2=CC(F)=C(F)C(F)=C2F)=O)C=C1
Biological Activity: NN-390 is a potent and selective HDAC6 inhibitor, with an IC50 of 9.8 nM. NN-390 penetrates the blood-brain barrier (BBB). NN-390 shows study potential in metastatic Group 3 MB (medulloblastoma)[1].
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NN-390 | NN-390 is a potent and selective HDAC6 inhibitor, with an IC50 of 9.8 nM. NN-390 penetrates the blood-brain barrier (BBB). NN-390 shows study potential in metastatic Group 3 MB (medulloblastoma). | |||||||||||||||||||||
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