2490468-31-8
2490468-31-8
Chemical Structure
HSV-1/HSV-2-IN-1
- CAS No.: 2490468-31-8
- Formula:C18H14F4N4OS
- Molecular Weight:410.39
IUPAC Name: (Z)-2-(1-ethyl-5-fluoro-2-oxoindolin-3-ylidene)-N-(4-(trifluoromethyl)phenyl)hydrazine-1-carbothioamide
InChIKey: NZHQLSKXTOUEKP-IWIPYMOSSA-N
SMILES: CCN1C(/C(C2=CC(F)=CC=C21)=N\NC(NC3=CC=C(C=C3)C(F)(F)F)=S)=O
Biological Activity: HSV-1/HSV-2-IN-1 (compound 7d) is a HSV-1 and HSV-2 inhibitor, with EC50s of 7.6, 7.6, 4, and 12 μM for HSV-1 (KOS), HSV-2 (G), HSV-1 TK- KOS ACVr and vaccinia virus in human embryonic lung fibroblast cell cultures[1].
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HSV-1/HSV-2-IN-1 | HSV-1/HSV-2-IN-1 (compound 7d) is a HSV-1 and HSV-2 inhibitor, with EC50s of 7.6, 7.6, 4, and 12 μM for HSV-1 (KOS), HSV-2 (G), HSV-1 TK- KOS ACVr and vaccinia virus in human embryonic lung fibroblast cell cultures. | |||||||||||||||||||||
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