2490538-26-4
2490538-26-4
Chemical Structure
Apoptotic agent-1
- CAS No.: 2490538-26-4
- Formula:C12H6ClN5O2S
- Molecular Weight:319.73
IUPAC Name: 5-chloro-4-(4-nitrophenyl)pyrimido[4,5-d]pyrimidine-2-thiol
InChIKey: YMOPNBMWCWYNCS-UHFFFAOYSA-N
SMILES: SC1=NC(C2=CC=C([N+]([O-])=O)C=C2)=C3C(N=CN=C3Cl)=N1
Biological Activity: Apoptotic agent-1 (Compound 8a) is an apoptotic agent with high antiproliferative activity against cancer cells and low cytotoxic effect. Apoptotic agent-1 induces over-expression of Fas receptor and Cyto C genes[1].
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Apoptotic agent-1 | Apoptotic agent-1 (Compound 8a) is an apoptotic agent with high antiproliferative activity against cancer cells and low cytotoxic effect. Apoptotic agent-1 induces over-expression of Fas receptor and Cyto C genes. | |||||||||||||||||||||
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