24915-04-6
24915-04-6
Chemical Structure
Sparteine
Synonym(s): Lupinidine
- CAS No.: 24915-04-6
- Formula:C15H26N2
- Molecular Weight:234.38
IUPAC Name: (7S,7aS,14S,14aS)-dodecahydro-2H,6H-7,14-methanodipyrido[1,2-a:1',2'-e][1,5]diazocine
InChIKey: SLRCCWJSBJZJBV-AJNGGQMLSA-N
SMILES: [H][C@]1(CN2[C@@]3([H])CCCC2)[C@@](CCCC4)([H])N4C[C@]3([H])C1
Biological Activity: Sparteine (Lupinidine) is an alkaloid compound derived from leguminous plants and can act as a ganglionic blocker. Sparteine competitively inhibits the activity of the neuronal nicotinic acetylcholine receptor (nACh receptor)[1][2].
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Sparteine | Sparteine (Lupinidine) is an alkaloid compound derived from leguminous plants and can act as a ganglionic blocker. Sparteine competitively inhibits the activity of the neuronal nicotinic acetylcholine receptor (nACh receptor). | |||||||||||||||||||||
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References
- [1]. Voitenko S, et al. Effect of (+)-sparteine on nicotinic acetylcholine receptors in the neurons of rat superior cervical ganglion. Mol Pharmacol. 1991 Aug;40(2):180-5. [Content Brief]
- [2]. Cook D, et al. The alkaloid profiles of Lupinus sulphureus. J Agric Food Chem. 2009 Feb 25;57(4):1646-53. [Content Brief]
