2492595-24-9
2492595-24-9
Chemical Structure
Nelremagpran
Synonym(s): MRGPRX4 modulator-2
- CAS No.: 2492595-24-9
- Formula:C15H9ClF4O3
- Molecular Weight:348.68
IUPAC Name: 3-((2-chloro-4-(trifluoromethyl)phenoxy)methyl)-2-fluorobenzoic acid
InChIKey: TWOXPNAILYKJPT-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC=CC(COC2=CC=C(C(F)(F)F)C=C2Cl)=C1F
Biological Activity: MRGPRX4 modulator-2 (compound 1-55) is a potent MRGPR X4 modulator, possessing antagonist activity against MRGPR X4 with an IC50 < 100 nM. MRGPRX4 modulator-2 can be used for researching autoimmune diseases such as psoriasis, multiple sclerosis, Steven Johnson’s Syndrome, and other chronic itch conditions[1].
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Nelremagpran | 99.94% | MRGPRX4 modulator-2 (compound 1-55) is a potent MRGPR X4 modulator, possessing antagonist activity against MRGPR X4 with an IC50 < 100 nM. MRGPRX4 modulator-2 can be used for researching autoimmune diseases such as psoriasis, multiple sclerosis, Steven Johnson’s Syndrome, and other chronic itch conditions. | ||||||||||||||||||||
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