2493426-43-8
2493426-43-8
Chemical Structure
HIV-1 inhibitor-43
- CAS No.: 2493426-43-8
- Formula:C24H21ClN2O4S
- Molecular Weight:468.95
IUPAC Name: 5-chloro-3-((3,5-dimethylphenyl)sulfonyl)-N-(2-hydroxybenzyl)-1H-indole-2-carboxamide
InChIKey: GHPUYKXSUPCAAC-UHFFFAOYSA-N
SMILES: O=C(C(N1)=C(S(=O)(C2=CC(C)=CC(C)=C2)=O)C3=C1C=CC(Cl)=C3)NCC4=CC=CC=C4O
Biological Activity: HIV-1 inhibitor-43 is a potent HIV-1 inhibitor with an EC50 of 21.3 nM, 6.2 nM, < 0.7 nM and < 0.7 nM for Y188L, K103N-Y181C, K103N and Y181C, respectively. HIV-1 inhibitor-43 can reduce HIV-1 RNA and protein p24 expression[1].
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HIV-1 inhibitor-43 | HIV-1 inhibitor-43 is a potent HIV-1 inhibitor with an EC50 of 21.3 nM, 6.2 nM, < 0.7 nM and < 0.7 nM for Y188L, K103N-Y181C, K103N and Y181C, respectively. HIV-1 inhibitor-43 can reduce HIV-1 RNA and protein p24 expression. | |||||||||||||||||||||
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