2494198-61-5
Chemical Structure
Miclxin
Synonym(s): DS37262926
- CAS No.: 2494198-61-5
- Formula:C26H27N5O2
- Molecular Weight:441.52
IUPAC Name: 7-methoxy-N-(3-methoxybenzyl)-2-(3-(pyridin-3-yl)pyrrolidin-1-yl)quinazolin-4-amine
InChIKey: OXSWPFXQCLRTCF-UHFFFAOYSA-N
SMILES: COC1=CC(CNC2=C3C=CC(OC)=CC3=NC(N4CC(C5=CC=CN=C5)CC4)=N2)=CC=C1
Biological Activity: Miclxin (DS37262926) is a potent inhibitor of mutant β-catenin, involving in Wnt signaling pathway. Miclxin induces β-catenin-dependent apoptosis, leads to severe mitochondrial damage with the loss of mitochondrial membrane. Miclxin kills tumor via targeting to MIC60, a major components of the mitochondrial contact site and cristae organizing system (MICOS) complex[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Miclxin | 98.12% | Miclxin (DS37262926) is a potent inhibitor of mutant β-catenin, involving in Wnt signaling pathway. Miclxin induces β-catenin-dependent apoptosis, leads to severe mitochondrial damage with the loss of mitochondrial membrane. Miclxin kills tumor via targeting to MIC60, a major components of the mitochondrial contact site and cristae organizing system (MICOS) complex. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
