2497687-47-3
2497687-47-3
Chemical Structure
Antiproliferative agent-7
- CAS No.: 2497687-47-3
- Formula:C28H32N4O
- Molecular Weight:440.58
IUPAC Name: 3-(4-(1-benzyl-4-phenyl-1H-1,2,3-triazol-5-yl)phenoxy)-N,N-diethylpropan-1-amine
InChIKey: DUQSWLLXMYNLOO-UHFFFAOYSA-N
SMILES: CCN(CC)CCCOC1=CC=C(C2=C(C3=CC=CC=C3)N=NN2CC4=CC=CC=C4)C=C1
Biological Activity: Antiproliferative agent-7 (compound 8f) is a potent anti-proliferative agent. Antiproliferative agent-7 has antiproliferative activity against cancer cell lines MCF-7, MDA-MB-231, HCT-116 and FR-2 with IC50s of 3.5 μM, 15.54 μM, 30.43 μM and 34.8 μM, respectively. Antiproliferative agent-7 can increase ROS production and induce apoptosis[1].
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Antiproliferative agent-7 | Antiproliferative agent-7 (compound 8f) is a potent anti-proliferative agent. Antiproliferative agent-7 has antiproliferative activity against cancer cell lines MCF-7, MDA-MB-231, HCT-116 and FR-2 with IC50s of 3.5 μM, 15.54 μM, 30.43 μM and 34.8 μM, respectively. Antiproliferative agent-7 can increase ROS production and induce apoptosis. | |||||||||||||||||||||
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