25006-32-0
25006-32-0
Chemical Structure
Leptophos oxon
- CAS No.: 25006-32-0
- Formula:C13H10BrCl2O3P
- Molecular Weight:396.00
IUPAC Name: 4-bromo-2,5-dichlorophenyl methyl phenylphosphonate
InChIKey: MAKUYRKZFGSMMG-UHFFFAOYSA-N
SMILES: O=P(C1=CC=CC=C1)(OC)OC2=CC(Cl)=C(Br)C=C2Cl
Biological Activity: Leptophos oxon, a metabolite of leptophos, is a GABAA receptor chloride channel inhibitor with an IC50 values of 89.6 μM. Leptophos oxon inhibits GABA-induced chloride influx, binds to GABAA receptor-associated TBPS sites, and inhibits TBPS binding to voltage-dependent chloride channels. Leptophos oxon is a insecticide. Leptophos oxon can be used for the research of neurological disease[2].
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Leptophos oxon | Leptophos oxon, a metabolite of leptophos, is a GABAA receptor chloride channel inhibitor with an IC50 values of 89.6 μM. Leptophos oxon inhibits GABA-induced chloride influx, binds to GABAA receptor-associated TBPS sites, and inhibits TBPS binding to voltage-dependent chloride channels. Leptophos oxon is a insecticide. Leptophos oxon can be used for the research of neurological disease. | |||||||||||||||||||||
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