2502095-64-7
2502095-64-7
Chemical Structure
CYP51/HDAC-IN-1
- CAS No.: 2502095-64-7
- Formula:C30H40F2N6O4
- Molecular Weight:586.67
IUPAC Name: 8-(4-((4-(2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl)piperazin-1-yl)methyl)phenoxy)-N-hydroxyoctanamide
InChIKey: OTKHPXIZGZXEAT-UHFFFAOYSA-N
SMILES: O=C(CCCCCCCOC1=CC=C(CN2CCN(CC(C3=CC=C(C=C3F)F)(CN4N=CN=C4)O)CC2)C=C1)NO
Biological Activity: CYP51/HDAC-IN-1 is a potent, orally active CYP51/HDAC dual inhibitor. CYP51/HDAC-IN-1 inhibits important virulence factors and down-regulated resistance-associated genes. CYP51/HDAC-IN-1 exhibits potent therapeutic effects for both tropical candidiasis and cryptococcal meningitis[1].
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CYP51/HDAC-IN-1 | CYP51/HDAC-IN-1 is a potent, orally active CYP51/HDAC dual inhibitor. CYP51/HDAC-IN-1 inhibits important virulence factors and down-regulated resistance-associated genes. CYP51/HDAC-IN-1 exhibits potent therapeutic effects for both tropical candidiasis and cryptococcal meningitis. | |||||||||||||||||||||
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