2504229-61-0
2504229-61-0
Chemical Structure
(R)-MALT1-IN-3
- CAS No.: 2504229-61-0
- Formula:C21H19F3N8O2
- Molecular Weight:472.42
IUPAC Name: (R)-1-(6-(2H-1,2,3-triazol-2-yl)-5-(trifluoromethyl)pyridin-3-yl)-3-(5-cyano-4-(cyclopropyl(methoxy)methyl)-6-methylpyridin-3-yl)urea
InChIKey: DDGNZGLBMAPNGD-GOSISDBHSA-N
SMILES: CO[C@H](C1CC1)C2=C(C#N)C(C)=NC=C2NC(NC3=CN=C(N4N=CC=N4)C(C(F)(F)F)=C3)=O
Biological Activity: (R)-MALT1-IN-3 (compound 121) is a potent MALT1 protease inhibitor with an IC50 of 20 nM. (R)-MALT1-IN-3 has IC50 of 60 nM, 40 nM for human IL6/IL10 in OCI-LY3 cells, respectively[1].
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(R)-MALT1-IN-3 | (R)-MALT1-IN-3 (compound 121) is a potent MALT1 protease inhibitor with an IC50 of 20 nM. (R)-MALT1-IN-3 has IC50 of 60 nM, 40 nM for human IL6/IL10 in OCI-LY3 cells, respectively. | |||||||||||||||||||||
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