2508026-62-6
2508026-62-6
Chemical Structure
NSC 15830 hydrochloride
Synonym(s): S-(1,2-Dichlorovinyl)-L-cysteine hydrochloride
- CAS No.: 2508026-62-6
- Formula:C5H8Cl3NO2S
- Molecular Weight:252.55
InChIKey: WWBANJWARDZMIB-PIKFLZLVSA-N
SMILES: N[C@@H](CS/C(Cl)=C/Cl)C(O)=O.Cl
Biological Activity: NSC 15830 (S-(1,2-Dichlorovinyl)-L-cysteine) hydrochloride is a nephrotoxin and metabolite of trichloroethylene. NSC 15830 hydrochloride inhibits pathogen-stimulated TNF-α[1][2][3].
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NSC 15830 hydrochloride | NSC 15830 (S-(1,2-Dichlorovinyl)-L-cysteine) hydrochloride is a nephrotoxin and metabolite of trichloroethylene. NSC 15830 hydrochloride inhibits pathogen-stimulated TNF-α. | |||||||||||||||||||||
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References
- [1]. Boldenow E, et al. The trichloroethylene metabolite S-(1,2-dichlorovinyl)-l-cysteine but not trichloroacetate inhibits pathogen-stimulated TNF-α in human extraplacental membranes in vitro. Reprod Toxicol. 2015 Apr;52:1-6. [Content Brief]
- [2]. Lash LH, et al. Multigenerational study of chemically induced cytotoxicity and proliferation in cultures of human proximal tubular cells. Int J Mol Sci. 2014 Nov 18;15(11):21348-65. [Content Brief]
- [3]. Yoo HS, et al. Comparative analysis of the relationship between trichloroethylene metabolism and tissue-specific toxicity among inbred mouse strains: kidney effects. J Toxicol Environ Health A. 2015;78(1):32-49. [Content Brief]
