2511247-29-1
Chemical Structure
Imdatifan
Synonym(s): HIF-2α-IN-7; NKT2152
- CAS No.: 2511247-29-1
- Formula:C18H9F6NO2
- Molecular Weight:385.26
IUPAC Name: (E)-2-bromo-4-(2-(3-(dicyanomethylene)-5,5-dimethylcyclohex-1-en-1-yl)vinyl)phenyl isonicotinate
InChIKey: ZIEZRTWLAIDXDH-BLLLJJGKSA-N
SMILES: O[C@]12C3=C(C(F)(C1(F)F)F)C=CC(OC4=CC(C#N)=CC(F)=C4)=C3[C@H](C2)F
Biological Activity: Imdatifan (HIF-2α-IN-7) is a hypoxia inducible factor 2α (HIF-2α) inhibitor. Imdatifan can inhibit HIF-2α with an EC50 value of 6 nM. Imdatifan can be used for the research of various types of diseases including cancer, liver disease, inflammatory disease, pulmonary diseases and iron load disorders[1].
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Imdatifan | Imdatifan (HIF-2α-IN-7) is a hypoxia inducible factor 2α (HIF-2α) inhibitor. Imdatifan can inhibit HIF-2α with an EC50 value of 6 nM. Imdatifan can be used for the research of various types of diseases including cancer, liver disease, inflammatory disease, pulmonary diseases and iron load disorders. | |||||||||||||||||||||
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