2511248-11-4

JNJ-74856665 Chemical Structure
2511248-11-4

Chemical Structure

JNJ-74856665

Synonym(s): DHODH-IN-16; JNJ-6665

  • CAS No.: 2511248-11-4
  • Formula:C24H25FN4O3
  • Molecular Weight:436.48

IUPAC Name: 6-(4-ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)-7-fluoro-4-isopropyl-2-(o-tolyl)isoquinolin-1(2H)-one

InChIKey: BZKHQYHQHLKJNX-UHFFFAOYSA-N

SMILES: O=C1C2=C(C(C(C)C)=CN1C3=C(C)C=CC=C3)C=C(N4N=C(CO)N(CC)C4=O)C(F)=C2

Biological Activity: JNJ-74856665 (DHODH-IN-16) is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 0.396 nM for human DHODH[1].

Cat. No. Product Name Purity Description Pricing
HY-139189
JNJ-74856665 99.74% JNJ-74856665 (DHODH-IN-16) is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 0.396 nM for human DHODH.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References