2512224-38-1
2512224-38-1
Chemical Structure
Raloxifene-d10 hydrochloride
Synonym(s): Keoxifene-d10 hydrochloride; LY156758-d10; LY139481-d10 hydrochloride
- CAS No.: 2512224-38-1
- Formula:C28H18D10ClNO4S
- Molecular Weight:520.11
InChIKey: BKXVVCILCIUCLG-TYCDPVSQSA-N
SMILES: OC1=CC=C(C(SC2=C3C=CC(O)=C2)=C3C(C4=CC=C(C=C4)OCCN5C([2H])(C([2H])(C([2H])(C([2H])(C5([2H])[2H])[2H])[2H])[2H])[2H])=O)C=C1.Cl
Biological Activity: Raloxifene-d10 (Keoxifene-d10) hydrochloride is the deuterated-labeled Raloxifene hydrochloride (HY-13738A). Raloxifene hydrochloride (Keoxifene hydrochloride) is a second generation selective and orally active estrogen receptor modulator. Raloxifene hydrochloride produces estrogen-agonistic effects on bone and lipid metabolism and estrogen-antagonistic effects on uterine endometrium and breast tissue[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Raloxifene-d10 hydrochloride | Raloxifene-d10 (Keoxifene-d10) hydrochloride is the deuterated-labeled Raloxifene hydrochloride (HY-13738A). Raloxifene hydrochloride (Keoxifene hydrochloride) is a second generation selective and orally active estrogen receptor modulator. Raloxifene hydrochloride produces estrogen-agonistic effects on bone and lipid metabolism and estrogen-antagonistic effects on uterine endometrium and breast tissue. | |||||||||||||||||||||
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Raloxifene hydrochloride (Standard) | 99.84% | Raloxifene (hydrochloride) (Standard) is the analytical standard of Raloxifene (hydrochloride). This product is intended for research and analytical applications. Raloxifene hydrochloride (Keoxifene hydrochloride) is a second generation selective and orally active estrogen receptor modulator. Raloxifene hydrochloride produces estrogen-agonistic effects on bone and lipid metabolism and estrogen-antagonistic effects on uterine endometrium and breast tissue. | ||||||||||||||||||||
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Raloxifene hydrochloride | 99.78% | Raloxifene hydrochloride (Keoxifene hydrochloride) is a second generation selective and orally active estrogen receptor modulator. Raloxifene hydrochloride produces estrogen-agonistic effects on bone and lipid metabolism and estrogen-antagonistic effects on uterine endometrium and breast tissue. | ||||||||||||||||||||
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LY117018 TFA | 99.18% | LY117018 TFA, a Raloxifene analog, is a selective estrogen receptor modulator. LY117018 TFA exerts antiproliferative effects on breast cancer cell lines. | ||||||||||||||||||||
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LY117018 (Standard) | ≥98% | LY117018 (Standard) is the analytical standard of LY117018. This product is intended for research and analytical applications. LY117018, a Raloxifene analog, is a selective estrogen receptor modulator. LY117018 exerts antiproliferative effects on breast cancer cell lines. | ||||||||||||||||||||
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Raloxifene Bismethyl Ether hydrochloride | Raloxifene Bismethyl Ether hydrochloride is a metabolite of Raloxifene and an estrogen receptor inactive compound on which both hydroxyl groups are absent. | |||||||||||||||||||||
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Raloxifene 6-Monomethyl Ether | Raloxifene 6-Monomethyl Ether (Compound 7) is a Raloxifene derivative that inhibits estrogen receptor α. Raloxifene 4-Monomethyl Ether inhibits MCF-7 cells with an IC50 of 250 nM and a pIC50 of 6.6. | |||||||||||||||||||||
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Raloxifene N-Oxide | Raloxifene N-Oxide is a Raloxifene oxidative degradation product. | |||||||||||||||||||||
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Raloxifene 4-Monomethyl Ether | Raloxifene 4-Monomethyl Ether (Compound 37) is a Raloxifene derivative that inhibits estrogen receptor α. Raloxifene 4-Monomethyl Ether inhibits MCF-7 cells with an IC50 of 1 μM and a pIC50 of 6. | |||||||||||||||||||||
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Raloxifene | 99.62% | Raloxifene (Keoxifene) is a benzothiophene-derived selective estrogen receptor modulator (SERM). Raloxifene has estrogen-agonistic effects on bone and lipids and estrogen-antagonistic effects on the breast and uterus. Raloxifene is used for breast cancer and osteoporosis research. | ||||||||||||||||||||
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Raloxifene alkene | Raloxifene alkene (Compound 101) is a serum cholesterol clearance agent. Raloxifene alkene has significant anti-proliferation activity against breast adenocarcinoma cells. Raloxifene alkene effectively reduces serum cholesterol level without significant uterine weight and increase of number oieosinoohils in the stromallaver of ovarleclomized rat models. Raloxifene alkene can be used for post-menopausasyndrome, particularly osteoporosis, estrogen-dependent breast and uterine carcinoma research. | |||||||||||||||||||||
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Raloxifene impurity 6 | Raloxifene impurity 6 is an impurity of Raloxifene. | |||||||||||||||||||||
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Raloxifene impurity 5 | Raloxifene impurity 5 is an impurity of Raloxifene. | |||||||||||||||||||||
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