2517682-14-1
2517682-14-1
Chemical Structure
(R)-NVS-ZP7-4
- CAS No.: 2517682-14-1
- Formula:C28H28FN5OS
- Molecular Weight:501.62
IUPAC Name: (R)-1-(2-((6-fluorobenzo[d]thiazol-2-yl)amino)-3-phenylpropyl)-1'H-spiro[piperidine-4,4'-quinazolin]-2'(3'H)-one
InChIKey: FZOFDZMKSAUTHT-OAQYLSRUSA-N
SMILES: O=C(NC12CCN(C[C@H](NC3=NC4=CC=C(F)C=C4S3)CC5=CC=CC=C5)CC2)NC6=C1C=CC=C6
Biological Activity: (R)-NVS-ZP7-4 is the R-isomer of NVS-ZP7-4. NVS-ZP7-4 is a Zinc transporter SLC39A7 (ZIP7) inhibitor that is also the first reported chemical tool to probe the impact of modulating ER zinc levels and investigate ZIP7 as a novel agentgable node in the Notch pathway.
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(R)-NVS-ZP7-4 | 98.80% | (R)-NVS-ZP7-4 is the R-isomer of NVS-ZP7-4. NVS-ZP7-4 is a Zinc transporter SLC39A7 (ZIP7) inhibitor that is also the first reported chemical tool to probe the impact of modulating ER zinc levels and investigate ZIP7 as a novel agentgable node in the Notch pathway. | ||||||||||||||||||||
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