252557-97-4
Chemical Structure
CH 5450
Synonym(s): Z-Ile-Glu-Pro-Phe-Ome
- CAS No.: 252557-97-4
- Formula:C34H44N4O9
- Molecular Weight:652.73
IUPAC Name: (S)-4-((2S,3S)-2-(((benzyloxy)carbonyl)amino)-3-methylpentanamido)-5-((S)-2-(((S)-1-methoxy-1-oxo-3-phenylpropan-2-yl)carbamoyl)pyrrolidin-1-yl)-5-oxopentanoic acid
InChIKey: NQFWNRFKRYMGAI-OXHJWIHTSA-N
SMILES: O=C(OC)[C@@H](NC([C@H]1N(C([C@@H](NC([C@@H](NC(OCC2=CC=CC=C2)=O)[C@@H](C)CC)=O)CCC(O)=O)=O)CCC1)=O)CC3=CC=CC=C3
Biological Activity: CH 5450 (Z-Ile-Glu-Pro-Phe-Ome) is a selective short peptide human cardiac chymase inhibitor. CH-5450 inhibits the action of rat MAB elastase 2 on substrate Ang I with an IC50 value of 49 µM and N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide with an IC50 value of 4.8 µM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
CH 5450 | 98.04% | CH 5450 (Z-Ile-Glu-Pro-Phe-Ome) is a selective short peptide human cardiac chymase inhibitor. CH-5450 inhibits the action of rat MAB elastase 2 on substrate Ang I with an IC50 value of 49 µM and N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide with an IC50 value of 4.8 µM. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
