2531396-44-6
Chemical Structure
HE4-1 leech peptide
- CAS No.: 2531396-44-6
- Formula:C59H96N16O25
- Molecular Weight:1429.49
InChIKey: VLHQHQHTRPXGIB-FASWOEOSSA-N
SMILES: O=C(N[C@@H](C)C(NCC(N[C@@H](CO)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(NCC(N[C@@H](CC(O)=O)C(N1[C@@H](CCC1)C(N[C@@H](C(C)C)C(N[C@@H](C)C(NCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCC(O)=O)N
Biological Activity: HE4-1 leech peptide is a p38 MAPK inhibitor with an additional c-Jun N-terminal kinase (JNK) inhibitory role. HE4-1 leech peptide suppresses macrophage migration, and does not significantly affect macrophage immunological activities including phagocytic ability, lysozyme activity, and expression levels of most inflammatory factors. HE4-1 leech peptide can be used for the research of atherosclerosis[1].
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HE4-1 leech peptide | HE4-1 leech peptide is a p38 MAPK inhibitor with an additional c-Jun N-terminal kinase (JNK) inhibitory role. HE4-1 leech peptide suppresses macrophage migration, and does not significantly affect macrophage immunological activities including phagocytic ability, lysozyme activity, and expression levels of most inflammatory factors. HE4-1 leech peptide can be used for the research of atherosclerosis. | |||||||||||||||||||||
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