2559759-40-7
2559759-40-7
Chemical Structure
ABCG2-IN-1
- CAS No.: 2559759-40-7
- Formula:C26H36N4O4
- Molecular Weight:468.59
InChIKey: MJLGVXCTSMTDEP-JBACZVJFSA-N
SMILES: CC(C)C[C@H]1C2=C(C[C@]3([H])N1C([C@@H](NC3=O)CCC(NC(C)(C)C)=O)=O)C4=CC=C(OC)C=C4N2
Biological Activity: ABCG2-IN-1 (compound K2), a Ko143 analog, is an orally active ABCG2 inhibitor with an IC50 of 0.13 μM. ABCG2-IN-1 has favorable oral pharmacokinetic profiles in mice[1].
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ABCG2-IN-1 | ABCG2-IN-1 (compound K2), a Ko143 analog, is an orally active ABCG2 inhibitor with an IC50 of 0.13 μM. ABCG2-IN-1 has favorable oral pharmacokinetic profiles in mice. | |||||||||||||||||||||
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