2568277-33-6
2568277-33-6
Chemical Structure
PROTAC SMARCA2/4 degrader-10
- CAS No.: 2568277-33-6
- Formula:C49H62N10O5S
- Molecular Weight:903.15
InChIKey: BTIYALWUSAHOOI-FPRWIQRKSA-N
SMILES: NC1=C(C=C(C2=C(C=CC=C2)O)N=N1)C3=CN(C4CCN(CC4)CC[C@@H]5CC[C@H](CC5)C(N[C@@H](C(C)(C)C)C(N6[C@@H](C[C@H](C6)O)C(NCC7=CC=C(C8=C(N=CS8)C)C=C7)=O)=O)=O)N=C3
Biological Activity: PROTAC SMARCA2/4-degrader-10 (compound I-399) is a potent SMARCA2 degrader with an DC50 value of ＜100 nM. PROTAC SMARCA2/4-degrader-10 has the potential for the research of cancer[1].
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PROTAC SMARCA2/4 degrader-10 | PROTAC SMARCA2/4-degrader-10 (compound I-399) is a potent SMARCA2 degrader with an DC50 value of ＜100 nM. PROTAC SMARCA2/4-degrader-10 has the potential for the research of cancer. | |||||||||||||||||||||
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