257277-05-7
Chemical Structure
Iseganan
Synonym(s): IB-367
- CAS No.: 257277-05-7
- Formula:C78H126N30O18S4
- Molecular Weight:1900.28
SMILES: O=C(N[C@]1([H])C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@@](C(N[C@H](C(N[C@@H](CSSC[C@@H](C(N2)=O)NC([C@H](CC(C)C)NC(CNC(CNC([C@@H](N)CCCNC(N)=N)=O)=O)=O)=O)C(N[C@@H](C(C)C)C(NCC(N[C@H](C(N)=O)CCCNC(N)=N)=O)=O)=O)=O)C(C)C)=O)([H])CSSC1)=O)CC3=CC=CC=C3)=O)CCCNC(N)=N)=O)=O)CCCNC(N)=N)=O)[C@@H]2CC4=CC=C(C=C4)O
Biological Activity: Iseganan is an anti-microbial peptide that is active against both Gram-positive and Gram-negative bacteria and fungi. Iseganan kills a broad-spectrum of bacteria and fungi by attaching to and destroying the integrity of the lipid cell membranes. Iseganan can be used for oral mucositis research[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Iseganan | 98.87% | Iseganan is an anti-microbial peptide that is active against both Gram-positive and Gram-negative bacteria and fungi. Iseganan kills a broad-spectrum of bacteria and fungi by attaching to and destroying the integrity of the lipid cell membranes. Iseganan can be used for oral mucositis research. | ||||||||||||||||||||
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References
- [1]. Toney JH. Iseganan (IntraBiotics pharmaceuticals). Curr Opin Investig Drugs. 2002 Feb;3(2):225-8. [Content Brief]
- [2]. Giles FJ, et al. Iseganan HCl: a novel antimicrobial agent. Expert Opin Investig Drugs. 2002 Aug;11(8):1161-70. [Content Brief]
- [3]. Landa A, et al. Antimicrobial peptides (Temporin A and Iseganan IB-367): effect on the cysticerci of Taenia crassiceps. Mol Biochem Parasitol. 2009 Apr;164(2):126-30. [Content Brief]
