2573782-74-6
2573782-74-6
Chemical Structure
B-Raf IN 13
- CAS No.: 2573782-74-6
- Formula:C19H19ClFN3O4S
- Molecular Weight:439.89
IUPAC Name: N-(2-chloro-3-((3,5-dimethyl-4-oxo-3,4-dihydroquinazolin-6-yl)oxy)-5-fluorophenyl)propane-1-sulfonamide
InChIKey: TUHRHIRPXIILLF-UHFFFAOYSA-N
SMILES: O=C1C2=C(C=CC(OC3=CC(F)=CC(NS(=O)(CCC)=O)=C3Cl)=C2C)N=CN1C
Biological Activity: B-Raf IN 13 is a BRAF inhibitor with an IC50 of 3.55 nM in BRAF V600E enzyme assay. B-Raf IN 13 has anticaner effects (WO2020261156A1, Example 74)[1].
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B-Raf IN 13 | B-Raf IN 13 is a BRAF inhibitor with an IC50 of 3.55 nM in BRAF V600E enzyme assay. B-Raf IN 13 has anticaner effects (WO2020261156A1, Example 74). | |||||||||||||||||||||
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