2573869-16-4
2573869-16-4
Chemical Structure
EGFR-IN-15
- CAS No.: 2573869-16-4
- Formula:C24H25BrN6O2
- Molecular Weight:509.40
IUPAC Name: (R,E)-56-bromo-11,26,7-trimethyl-52,53-dihydro-11H,51H-11-oxa-4-aza-5(2,1)-benzo[d]imidazola-2(2,4)-pyridina-1(4,5)-pyrazolacycloundecaphan-3-one
InChIKey: UPMBIKXABDDVHH-CQSZACIVSA-N
SMILES: C[C@H]1CN2C3=CC(Br)=CC=C3N/C2=N\C(C4=CC(C)=NC(C5=C(N(N=C5)C)OCCC1)=C4)=O
Biological Activity:
EGFR-IN-15 is an EGFR inhibitor with an IC50 of 4 nM. EGFR-IN-15 exhibits an IC50 of 16 nM against Osimertinib (HY-15772)-resistant mutant EGFR such as L858R/T790M/C797S. EGFR-IN-15 can be used for research on oncological diseases[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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EGFR-IN-15 | 96.21% | EGFR-IN-15 is an EGFR inhibitor with an IC50 of 4 nM. EGFR-IN-15 exhibits an IC50 of 16 nM against Osimertinib (HY-15772)-resistant mutant EGFR such as L858R/T790M/C797S. EGFR-IN-15 can be used for research on oncological diseases. |
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