2574524-67-5
Chemical Structure
Soficitinib
- CAS No.: 2574524-67-5
- Formula:C18H21ClN8O
- Molecular Weight:400.87
IUPAC Name: 3-((3aS,6aR)-5-(5-chloro-2-((1-methyl-1H-pyrazol-4-yl)amino)pyrimidin-4-yl)-3a-methylhexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)-3-oxopropanenitrile
InChIKey: OWDNRVGFIXZHAC-KPZWWZAWSA-N
SMILES: C[C@]12[C@](CN(C2)C(CC#N)=O)([H])CN(C3=NC(NC4=CN(C)N=C4)=NC=C3Cl)C1
Biological Activity: Soficitinib (Compound 20) is a selective tyrosine kinase 2 (TYK2) and Janus kinase 2 (JAK2) inhibitor, with IC50 values of 0.5 nM and 1.2 nM, respectively. Soficitinib shows promise for research into autoimmune diseases (such as psoriasis, rheumatoid arthritis) and inflammatory diseases[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Soficitinib | 98.54% | Soficitinib (Compound 20) is a selective tyrosine kinase 2 (TYK2) and Janus kinase 2 (JAK2) inhibitor, with IC50 values of 0.5 nM and 1.2 nM, respectively. Soficitinib shows promise for research into autoimmune diseases (such as psoriasis, rheumatoid arthritis) and inflammatory diseases. | ||||||||||||||||||||
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