2576358-68-2
Chemical Structure
Spermine Prodrug-1
- CAS No.: 2576358-68-2
- Formula:C24H45Cl3N4O5
- Molecular Weight:576.00
IUPAC Name: N-(3-((4-((3-aminopropyl)amino)butyl)amino)propyl)-3-(4,5-dimethoxy-2-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl)-3-methylbutanamide trihydrochloride
InChIKey: LNERPLLMHDYJTB-UHFFFAOYSA-N
SMILES: COC1=C(C(C(C(C)(CC(NCCCNCCCCNCCCN)=O)C)=C(C1=O)C)=O)OC.[H]Cl.[H]Cl.[H]Cl
Biological Activity: Spermine precursor-1 (Compound 1) is a redox-sensitive spermine precursor for the potential research of snyder robinson syndrome. Spermine precursor-1 inhibits wild-type (CMS-24949) and spermine synthase gene (SMS) mutant (CMS-26559, and CMS-6233) fibroblast cells with IC50s of 326.7, 198.5, and 244.1 μM, respectively[1].
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Spermine Prodrug-1 | Spermine precursor-1 (Compound 1) is a redox-sensitive spermine precursor for the potential research of snyder robinson syndrome. Spermine precursor-1 inhibits wild-type (CMS-24949) and spermine synthase gene (SMS) mutant (CMS-26559, and CMS-6233) fibroblast cells with IC50s of 326.7, 198.5, and 244.1 μM, respectively. | |||||||||||||||||||||
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